Clinicopathological correlation of ovarian tumors in a tertiary care hospital

Introduction and Objective: Ovary is one of the complex organs in terms of its embryology, histology, steroidogenesis and tumor incidence. The present study highlights the correlation between the clinical and pathological features of neoplastic lesions of ovary in order to arrive at a better understanding of the disease process. The objective of study is to assess the overall incidence of various histological types of ovarian neoplasm, the pattern of occurrence of ovarian tumors in relation to age, parity and modes of presentations and to study the histopathological findings of various ovarian tumors. Materials and Methods: Biopsies received at the Department of Pathology, Sree Balaji Medical College and Hospital-Chrompet were subjected for histopathological study. Specimens were then fixed in 10% formalin for 24-48 hour, processed and embedded in paraffin blocks. Sections of 4-6 microns thickness were taken and stained with routine haematoxylin and eosin and studied. IHC was done whenever necessary. Result: Out of 92 cases of ovarian tumors 68 cases were benign, 3 were borderline and 21 were malignant. Serous cystadenoma formed the majority (38%) among benign lesions and among malignant lesions serous cystadeno carcinoma (5.4%) were common. Majority were surface epithelial tumors and constituted 64.13% (59 cases) with germ cell tumors 26% (24 cases) and sex cord stromal tumors 8.6% (8 cases). Interpretation and Conclusion: The correct histopathological diagnosis of ovarian tumor is of prime importance in view of their behavioural predictability, clinical correlation and the proper management of patient.