The Association of Fasting Plasma Glucose and HbA1c in Type-2 Diabetes mellitus Patients: Implications for glycaemic Control

"ABSTRACT The dramatic increase in the incidence and prevalence of type-2 diabetes mellitus in both developed and developing worlds, putting pressure on healthcare resources, and will be more impacting on the developing world. Diabetes management often started later in the disease due to the asymptomatic nature of the disease , currently the available approach to the management of this disorder include lifestyle changes and hypoglycaemic medications present some shortcomings that keep the patient asking “Isn’t there anything new to manage my diabetes”(1)Glycaemic control traditionally relies on the measurement of fasting plasma glucose(FPG) now replaced with the glycated haemoglobin measurement and it is the gold standard as it offers more advantages over the traditional fasting plasma glucose measurement. Objectives:The present study is to determine the correlation between fasting plasma glucose and glycated haemoglobin in type-2 diabetes mellitus patients and its implications for better glycaemic control. Methods:In a retrospective cohort design the data of 395 known type-2 DM patients attending Asian Institute of Gastroenterology who had their HbA1c and FPG determined was analyzed to determine the carl Pearson correlation co-efficient(r) for the HbA1c and FPG. Results: shows that The result shows that the mean age of patients in this study is 51-56±10, the mean FPG is 137±50, and the mean HbA1c is 7.5%±1.5%. (see table 1) The Carl Pearson correlation co-efficient between HbA1c and FPG r=0.609. Conclusions: The positive correlation between HbA1c and FPG in type-2 diabetes mellitus patients suggest the importance of FPG as second line test for the blood glucose monitoring in resource limited settings most commonly found in developing countries. "