Potential Antifungal Activity of Fresh Garlic Cloves (Allium sativum L.) from Sudan

The incidences of fungal infections are increasing due to the growing phenomena of antifungal resistance and a limited number of antifungal drugs. As some fungi adversely affect on human health such as Candida albicans, or on its economic plants such as Aspergillus niger. In the current study, minced cloves of garlic from the Sudanese variety was tested against two referenced fungi, namely Aspergillus niger ATCC®6275TM and Candida albicans ATCC®10231TM. The results showed that garlic has a noticeable and high antifungal activity against both fungal strains, the inhibition zones of garlic were 41.0±4.0 mm and 28.0±1.0 mm, respectively, compared with clotrimazole which was 22.5±1.5 mm and 27.5±0.5 mm, respectively. This antifungal activity was statistically significant. Though, the fresh minced cloves of garlic was a competitor to that antifungal drug. With the available data, it can be concluded that garlic bulb is a potent antifungal agent.