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Evaluation of Anti-Inflammatory Activity of Methanolic Extract of Fruits of Solanum Xanthocarpum Schrad & Wendl in Albino Rats

Journal: International Research Journal of Pharmacy and Medical Sciences (IRJPMS) (Vol.1, No. 6)

Publication Date:

Authors : ;

Page : 1-5

Keywords : Anti-inflammatory; methanolic extract; solanum xanthocarpum.;

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Objective: To evaluate the anti-inflammatory activity of methanolic extract of Solanum Xanthocarpum in albino rats. Materials and Methods: Methanolic extract in the dose of 100,200,400mg/kg and aspirin in the dose of 100mg/kg was administered orally in different groups of albino rats to study their effect on inflammation induced by carrageenan or a foreign body. Aspirin100mg/kg and extract 400mg/kg was administered to study their interaction. Results: Methanolic extract of fruits of solanum xanthocarpum produced significant anti-inflammatory activity in acute and subacute inflammation models and was comparable to that of aspirin. The extract also potentiated the anti-inflammatory action of aspirin. Conclusion: Methanolic extract of fruits of solanum xanthocarpum possess significant anti-inflammatory activity

Last modified: 2018-11-10 21:43:57