Nanoparticulate system for cancer therapy: An updated review

Nowadays, pharmaceutical nanotechnology has been developed as the most emerging branch in the field of pharmacy. “Nanotechnology refers to the nanosize formulation. These nanoformulations may be used in treatment of various life-threading diseases like cancer. Due to the advantages of their nano size and shape, nanoformulations have been shown to be favorable drug delivery systems and may be useful for encapsulating and conjugating of drugs, enabling most precise tumor targeting and controlled release. Nanoparticle drug delivery system have several advantages such as enhanced intracellular infi ltration, hydrophobic solubility, and drug circulation time and also reduce nonspecifi c uptake and toxic effect for cancer therapy. A large number of Nanoparticle technologies have been developed for cancer treatment to improve the therapeutic effi cacy and safety for anticancer drugs. In this paper, we review the most signifi cant advancement in pharmaceutical nanotechnologies with methods of preparation and their usein drug delivery for cancer therapy.