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Survival Analysis of HIV Infected People on Antiretroviral Therapy at Mizan-Aman General Hospital, Southwest Ethiopia

Journal: International Journal of Science and Research (IJSR) (Vol.3, No. 5)

Publication Date:

Authors : ; ; ;

Page : 1462-1468

Keywords : ART; Survival analysis; Cohort; Retrospective; Ethiopia.;

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Provision of intervention with antiretroviral therapy has significantly changed the course of the AIDS epidemic form to less life-threatening chronic disease. Thus, the study was aimed at assessing the survival and risk factors of death in people living with HIV/AIDS after initiation of antiretroviral therapy at the Hospital.A retrospective cohort study design was applied in this study. The cohort was stratified into three age groups: children, adolescents, and adults.Kaplan-Meier method was effectively run to estimate survival after initiation of ART. Hazard ratio and Cox proportional-hazard regression model were used to determine predictors of survival time to death. The cumulative probability of survival time at the 6th months after initiation of ART was 96% and 94%, 96% and 96% for children, adolescents and adults respectively (95%CI). Mortality was significantly higher among patients with a low initial CD4, advanced WHO clinical disease stage III and IV,INH Prophylaxis, TB infection and bedridden. The present study has shown that there has been low cumulative incidence of mortality for HIV patients. Higher priority should be given to HIV-infected individuals by starting ART therapy during the preliminary stage of their illness.

Last modified: 2014-07-03 16:33:26