Pancreas Sparing Duodenectomy for Gastro Intestinal Stromal Tumour - A case report and review of literature

Duodenal gastrointestinal stromal tumors (GISTs) are uncommon and constitute a relatively small subset of GISTs which presents a unique dilemma having various surgical options. Two cases of large duodenal GISTs one complicated by massive GI bleed and the other complicated by iatrogenic rupture, arising from the third and fourth parts of the duodenum and not involving the pancreas which was managed by a pancreas sparing duodenal resection is presented. The literature is also reviewed to present the current status on surgical options, outcome, prognostic indicators and the role of Imatinib mesylate in its management.