EFFICACY OF KARPOORA SILASATTHU PARPAM IN THE MANAGEMENT OF AZHAL KALLADAIPPU (RENAL CALCULI)

Background: Kalladaippu (Kidney stones) is a common problem worldwide with substantial morbidities and economic costs. A large number of people are suffering from urinary stone problem all over the globe. Kidney stones are excruciatingly painful and primarily affect people who are of working age. These patients face not only the cost of treatment, but also the financial difficulties from time off work due to pain and treatment. Recurrent stone formation is a common problem with all types of stones and therefore an important part of the medical care of patients with stone disease. Siddha system of medicine is a great way to treat kidney stones over the years. Siddha formulations indicated for urolithiasis in ancient siddha literatures may have potential antiurolithiatic activity in animal models and also clinically effective in the management of Urolithiasis. Objective: To evaluate the therapeutic efficacy of a siddha formulation KarpooraSilasathuparpam in the treatment of AzhalKalladaippu (Renal Calculi). Method: It is an open clinical trial conducted in OPD of AyothidossPandithar Hospital, National Institute of siddha, Chennai for a period of one year. 40 patients diagnosed as AzhalKalladaippu (renal calculi) were included in this study based on the inclusion and exclusion criteria. The test drug Karpoorasilasathuparpam 130 mg was administered with 5ml of Radish juice orally two times a day after food for 48 days. Result: The mean? standard deviation of renal calculi at before and after treatment were 8.30 ? 3.16 and 4.2 ? 4.03 respectively which is statistically significant (t= 6.092 p<0.001). Conclusion:The herbo mineral siddha medicine, karpoora silasathu parpam posses the therapeutic effect on renal stone and it is a cost effective siddha formulation will be used in the treatment of early detected kidney stone >10mm without marked obstruction and could avoid surgical intervention.