GASTROPROTECTIVE AND ULCER HEALING ACTIVITY OF ETHANOLIC EXTRACT OF ADIANTUM LUNULATUM

Adiantum lunulatum is a fern found in monsoon season in Western Ghats, which is being used traditionally for many ailments such as bronchitis, cough, erysipelas and bleeding disorders. Aim of the present study was to investigate traditional claim of treating bleeding disorder and ulcer healing property of this plant. In the current study, ethanolic extract of adiantum lunulatum (500mg/kg) was evaluated for its efficacy in treating gastric ulcer in wistar albino rats. Ulcers were induced by different ulcer inducing models such as pylorus ligation induced ulcer, ethanol induced ulcer, cold restrain induced ulcer and aspirin induced ulcer. Omeprazole was used as a standard drug at a dose of 20mg/kg. Adiantum lunulatum showed a significant reduction in gastric ulcer, which was significantly comparable to standard drug omeprazole.