Methods and means of asymutal-invariant muller matrix polyarimetry of optical and anisotropic biological layers

Objectives: The work is aimed at the theoretical substantiation and experimental development of the azimuthally invariant polarimetry method of partially depolarizing optical anisotropic biological layers on the basis of coordinate Muller-matrix mapping of histological sections for differential diagnostics of changes in optical anisotropy, which are associated with the emergence of pathological states. Results: The method of azimuthally invariant Muller-matrix mapping of optically anisotropic samples of the myocardium is proposed and grounded. The values of azimuthally invariant matrix element, superposition of matrix elements and the magnitude of the matrix vector distributions are obtained. Conclusion: The magnitude of the 1st-4th order statistical moments' dependences, which characterize the distribution of the Muller-matrix invariant (MMI) of the histological sections of the myocardium are determined. The study of the possibility of differentiating causes of death due to ischemic heart disease (IHD) and acute coronary insufficiency (ACI) conducted from the standpoint of evidence-based medicine.