CLINICOPATHOLOGICAL STUDY OF NEOPLASTIC LARYNGEAL LESIONS IN A TERTIARY CARE HOSPITAL IN KASHMIR

Background:The larynx is affected by a range of benign and malignant lesions ,on account of its unique position in the upper respiratory tract which makes it vulnerable to many noxious stimuli. This study was undertaken to explore clinicopathological parameters in laryngeal cancers as laryngeal lesions are coming up to be the most common head and neck lesions in Kashmir. Methods :A one and a half year observational study was done(2015-2017).All layngectomies and biopsies received in the department were studied. Results: A total number of 68 neoplastic lesions were studied .The neoplastic lesions showed a peak after 50 years. Squamous cell carcinoma was present in 23.5% cases and was the commonest neoplastic lesion ,Moderately differentiated squamous cell carcinoma was the commonest differentiation(66.7%) . The most common site of involvement was the Glottis (62.5%) of cases. Out of the 11 laryngectomies, 3 cases showed perineural invasion,5 cases showed lymphovascular invasion . Conclusion:Light microscopy and histopathological examination remains the mainstay and gold standard in diagnosing benign and malignant lesions in larynx.