Carcinoma of Vagina in Women with Utero Vaginal Prolapse: Presentation of Two Cases and the Review of Literature

Primary vaginal cancer in women with utero vaginal prolapse is an uncommon entity. We report two women with longstanding third degree prolapse presented with ulcerated lesions. Both had vaginal hysterectomy and anterior colporrhaphy. Histology revealed moderately differentiated squamous cell carcinoma. One woman developed advanced malignancy in three months of surgery and the other is surviving after five years. The latter developed a lesion in the vagina recently and biopsy revealed poorly differentiated squamous cell carcinoma. Review of the literature and personal experience suggest that vaginal hysterectomy and repair should be offered to women developing utero vaginal prolapse as when longstanding chances of developing cancer of vagina becomes significant.