Review: Five and Six Membered Heterocyclic Compound with Antimicrobial Activity

Bacterial and fungal infections have been for many centuries a major cause of death in humans. It was found in late 19th century that many common diseases are caused by microscopic pathogens which led to introduction of antiseptic procedures in order to diminish mortality related to postsurgical infections. Compounds classified as heterocyclic probably constitute the largest and most varied family of organic compounds. Among heterocyclic compounds five-membered heterocycles constitute a wide and differentiated group with broad spectrum of biological activity. Compounds from this class are present in nature as constituents of nucleic acids, some important amino acids, alkaloids and hormones. This paper presents the information regarding the Heterocyclic compounds that constitute the largest family of organic compounds. These are extremely important with wide array of synthetic, pharmaceutical and industrial applications