Histopathology of nephrectomy specimens: A ten year south Indian tertiary hospital based study

Introduction: Nephrectomies are an integral part of urological practice and a wide range of renal diseases are seen on histopathological examination of nephrectomy specimens. Aim: This study was conducted to evaluate the neoplastic and non neoplastic conditions encountered in nephrectomy specimens that were received in our department over a ten year period and compare it with other studies. Materials and Methods: A hospital-based ten year retrospective study of all nephrectomy specimens received in the department of Pathology. Results: A total of 177 nephrectomy specimens were studied. 54.3% cases were male patients with peak during 5th-6th decade. 63.8% cases were non neoplastic lesions and 36.2% neoplastic lesions. Conclusion: Inflammatory causes more commonly required a nephrectomy in this study. The commonest indication for nephrectomy was chronic pyelonephritis followed by clear cell renal cell carcinoma.