Study of effect of exchange transfusion in pre-term and term infants: A prospective study

Hyperbilirubinemia is usually benign in preterm and term infants. Dangerous hyperbilirubinemia is uncommon but may cause long term neurological impairment. In a resource limited rural setup exchange transfusion is an easy, cheap and convenient way for treatment. Our Study focus to improve the outcome in neonatal Hyperbilirubinemia patients in a rural referral center of Odisha. Aim: Our present study aims at determining the alternations of various haematological and biochemical parameters after exchange transfusion along with adverse outcomes in pre-term and term infants. Materials and Methods: Total 106 new-borns blood samples were taken from those who have under gone exchange transfusion for different indications. New-borns are divided into two groups pre-term and term infants. Results: A significant decrease in serum bilirubin values was observed in both the groups after exchange transfusion. Also a significant decrease in blood platelet and increase in calcium level were also present. Conclusion: Proper approach and prompt management is needed in case of neonatal-hyperbilirubinemia in a resource limited rural setup.