SPINAL LYMPHOMA

Lymphoma is a lymphoreticular neoplasm primarily arises in extraskeletal location and skeletal involvement is secondary.skeletal lymphoma commonly seen at thoracic , lumbar and cervical spine.Primary bone lymphoma (PBL) comprises less than 5 percentage of all malignant bone tumors and almost 7 percentage of all extranodal lymphomas. Only 1.7 percentage of all PBLs have been reported to involve the vertebrae. In Hodgkin's lymphoma, approximately 90 percentage of the cases originate from lymph nodes, whereas 10 percentage arise from extranodal regions. In less than 0.25 percentage of patients with Hodgkin's disease there is primary extranodal presentation.Extranodal non-Hodgkin's lymphoma (NHL) accounts for 24-48 percentage of all NHL, while PSEL comprises 0.9 percentage of all extranodal NHLs. C l i n i c l l a y t h e y p r e s e n t w i t h p a i n a n d neurological manifestation. In skeletal Hodgkin s lymphoma shows vertebral sclerosis where as NHL shows permeative distruction is common. In our case patient presented with numbness on both lower limbs for 4days. Xray revealed paravertebral soft tissue density of D7 with decreased vertebral height . MRI shows altered marrow signal intensity with paravertebral and epidural soft tissue intensity lesion appears T1 hypointense and T2 hyperintense compressing the spinal cord at D7 level. Similar lesion also seen at L5 vertebra. Spinal lymphoma described in this study is a rare presentation with present MRI findings of marrow signal intensity and soft tissue abnormality and epidural component with sequale of mass effect on spinalcord.