Drugs Use or Abuse; Pharmacological Considerations | Biomedgrid

The most common and essential aspects of patient care when emergencies or urgencies have arisen consist of a thorough primary assessment of the patient and airway treatment. Once this is accomplished the need for drug administration and possible EMS (emergency medical service) assistance is determined. There are no reports of toxicities from degradation products of currently available drugs. How much of potency retain varies with the drug, the lot and the storage conditions, temperature, especially humidity, but many drugs stored under reasonable conditions in their original unopened containers retain ninety percent of their potency for at least three to five years after the expiration date on the label, and sometimes much longer.(with exception of Biological Pharmaceutical Products) Drugs in solution, particularly injectable that have become clear, transparent, cloudy or discolored or show signs of precipitation, should not be used [1]. Generally drugs are an important cause of liver injury. More than nine hundred drugs, toxins, and herbs have been reported to cause liver injury, and drugs account for twenty to forty percent of all instances of fulminate hepatic failure. Approx. seventy-five percent of the idiosyncratic reactions result in liver transplantation or death.