SYNTHESIS OF A NEW DERIVATIVE OF COLCHINE WITH PROPYLETHYNYLCARBINOL

A new method for the synthesis of a colchamine derivative with propylethynylcarbinol is proposed. The resulting substance was identified by thin layer and paper chromatography of 4- (colchamino N / 1-propylbutin2) carbinol. The structures of the synthesized compound are confirmed by the data of IR and PMR spectra. The resulting compounds are light yellow powders with close Rf values. At the same time, they are very different in chromatographic mobility from the original colchamine, having high Rf values