Effect of Intermittent Pneumatic Compression (IPC) on Glucose Regulation and Inflammation in Type 2 Diabetes | Biomedgrid

Purpose: The purpose of this study is to determine whether the intermittent pneumatic compression (IPC) device improves glucose regulation and inflammation in participants with type 2 diabetes. It was hypothesized that the intermittent pneumatic compression device will have positive effects on glucose regulation and inflammation in individuals with type 2 diabetes. Methods: Subjects included 10 individuals diagnosed with type 2 diabetes. Baseline measures of lipid profile and HbA1C were obtained by a finger stick. Plasma and serum were obtained intravenously to analyze insulin, glucagon, Interleukin 6 (IL-6) and C-reactive protein (CRP). The subjects came in a total of 3 times to the laboratory to be measured for the variables previously listed. The subjects completed a total of 35, IPC treatments (5 days/week for 7 weeks) by using the Norma Tec recovery system (NT). Results: No significant differences found within lipid profile or inflammation. CRP values decreased from the 1st to the 3rd treatment, but nosignificant difference was found. HbA1C was found significant (p = .002, p = .026) from 1st to 2nd and 1st to 3rd treatments. Conclusion: Previous research has shown an increase in blood flow from the use of the IPC devices. An increase in blood flow to the lower extremities can lead to positive effects in endothelial function, decreased inflammation and with further research, a decrease in HbA1C and other glucose regulators