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Unusual cause for secondary Hemophagocytic lymphohistiocytosis in children

Journal: University Journal of Medicine and Medical Specialities (Vol.5, No. 8)

Publication Date:

Authors : ;

Page : 35-36

Keywords : Hepatitis A infection; hemophagocytic lymphohistiocytosis; children;

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Hemophagocytic lymphohistiocytosis (HLH) is a syndrome characterized by high fever, maculopapular rash, neurological symptoms, abnormal liver functions and coagulopathy. Primary HLH is due to an underlying genetic abnormality. Secondary HLH are due to an underlying infection, autoimmune disease or malignancy. Secondary HLH due to viral infections are commonly due to the herpes group commonest of which is the Ebstein Barr virus (EBV). We describe two children with virus associated hemophagocytic lymphohistiocytosis (VAHLH) secondary to hepatitis A infection

Last modified: 2019-12-06 16:31:13