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Rare case of NK-T cell Lymphoma of tonsil in a young male - A case report

Journal: University Journal of Surgery and Surgical Specialities (Vol.6, No. 2)

Publication Date:

Authors : ;

Page : 113-115

Keywords : NK-T cell lymphoma; tonsil; chemotherapy; male;

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Abstract

Extranodal natural killer NK-T cell lymphoma, nasal type, is a predominantly extranodal lymphoma associated with Epstein-Barr virus occurring most frequently in the upper aerodigestive tract. It is mostly seen in men in the 6th decade of life. The lesions are usually locally destructive usually confined to the midline of nose and paranasal sinuses. Biopsy with immunohistochemistry analysis reveals CD 3, CD56 positive lymphoid cells with positive EBV markers. Early stages are treated with chemotherapy and radiotherapy with good results however the relapse rates are high with median survival rate being 12.5 months and less than six months in disseminated disease. We report a rare case of extranodal nasal type NK-T cell lymphoma of tonsil in a young male who responded well to combined therapy with CHOP regimen chemotherapy followed by radiotherapy and is in complete remission since 1 year.

Last modified: 2020-03-03 16:07:10