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N,N,N',N'-Tetramethyl-N,N'-bis(sulfo)ethane-1,2- Diaminium Mesylate ‎as a Highly Effective and Dual-functional Catalyst for the Synthesis of 1-Thioamidoalkyl-2-naphthols

Journal: Chemical Methodologies (Vol.4, No. 4)

Publication Date:

Authors : ; ; ; ; ;

Page : 400-407

Keywords : N; N; N'; N'-tetramethyl-N; N'-bis(sulfo)ethane-1; 2-diaminium mesylate ‎‎([TMBSED][Oms]2)‎; ‎Thioacetamide; 1-Thioamidoalkyl-2-naphthol; Multi-component ‎reaction; Dicationic ionic liquid; Dual-functional ‎catalyst.‎;

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Abstract

N,N,N',N'-tetramethyl-N,N'-bis(sulfo)ethane-1,2-diaminium mesylate ‎‎([TMBSED][Oms]2) is ‎used as a highly efficient and dual-functional catalyst for the one-pot multi-component ‎condensation of 2-naphthol with arylaldehydes and thioacetamide under green, mild (70 °C), ‎and solvent-free conditions. In this reaction, 1-thioamidoalkyl-2-naphthols are produced in ‎high to excellent yields and in relatively short reaction times. In this reaction, products ‎are identified by analysis of its 1H NMR, 13C NMR, and FT-IR data.‎ Moreover, a plausible mechanism based on dual-functionality of the catalyst was proposed.

Last modified: 2020-04-17 05:03:19