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Neurovascular pathophysiological targets of rosacea

Journal: Scientific review, Науковий огляд, Научное обозрение (Vol.5, No. 68)

Publication Date:

Authors : ;

Page : 19-36

Keywords : rosacea; neurovascular component; pathophysiological targets.;

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Abstract

The subject of the study – rosacea. The purpose of the work is to determine the pathophysiological targets for the development of clinical manifestations of rosacea. A survey of 47 women with rosacea is presented, and a comparative statistical analysis of significant differences in patients in the age groups before and after 40 years was not revealed for most of the factors that provoked the onset of dermatosis and its first clinical manifestations. These two groups differed in the duration of the disease and its forms (stages). The main structural and functional unit of the occurring lesions in rosacea is the neurovascular complex, and at least 16 pathophysiological “targets” have been identified from which various clinical manifestations of the disease can begin.

Last modified: 2020-07-13 00:27:13