Acantholytic Squamous Cell Carcinoma of Scalp: A Rare Case Report

Acantholytic squamous cell carcinoma (SCC) is an uncommon histopathological variant of SCC characterised by acantholysis of neoplastic cells, producing pseudo-lumina and appearance of glandular differentiation. It is also called pseudo-vascular adenoid SCC or pseudo-glandular SCC or pseudoangiosarcomatous SCC. This tumormimics the histopathological appearance of vascular neoplasm, particularly angiosarcoma.We describe a case of Acantholytic SCC in a fair-skinned 63 years old male construction worker to highlight the clinic-pathological features,as well as the recurrence and aggressiveness of this rare form of cutaneous SCC and demonstrate the difficulties in establishing the correct diagnosis.