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An Interesting Case Presentation of Burkitt Lymphoma Presenting with Lactic Acidosis and Thrombocytopenia

Journal: Journal of Clinical Case Studies (Vol.5, No. 2)

Publication Date:

Authors : ;

Page : 1-4

Keywords : Burkitt lymphoma; Non-Hodgkin lymphoma; Hyper-CVAD; Sepsis; Lactic acidosis;

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Burkitt Lymphoma (BL) is a very aggressive B-cell lymphoma caused by the translocation and subsequent dysregulation of the c-Myc gene on chromosome 8. There are 3 distinct clinical forms of Burkitt Lymphoma: endemic (African), sporadic (non-endemic), and immunodeficiency associated. Although these forms differ in their clinical presentation and their epidemiology, they share the same aggressive clinic behavior and are histological identical. This case presentation reports a rare case of sporadic form of BL clinically manifesting as sepsis in an immunocompetent young adult male. A quick diagnosis with bone marrow biopsy leads to starting treatment with IV chemotherapy. Unfortunately, our patient succumbed to the disease. It is necessary to consider malignancies as one of the main differential diagnosis to facilitate the correct diagnosis and prompt treatment.

Last modified: 2020-08-28 22:09:59