EVALUATION OF DOSIMETRIC PARAMETERS FOR ADOLESCENT CRANIOSPINAL IRRADIATION

Background: Craniospinal irradiation (CSI) is an important and challenging radiotherapy technique used for the treatment of Medulloblastoma, one of the most common pediatric cancers. Pediatric patients present with wide variability in weight, height, spine length, brain diameter, body size, intra and inter fractional motion depending on their age as compared to adults. These parameters have significant impact on radiation dose delivery to target and normal structures during radiotherapy of pediatric cancer patients. The present study was aimed to evaluate dosimetric parameters and generate plan quality indices for adolescent CSI. Materials and Methods: A 17 years old male adolescent patient with Medulloblastoma was recruited in the present sturdy. The patient was planned with RapidArcTM/ Volumetric Modulated Arc Therapy (VMAT) mode using 6 MV X-Ray photon beam from Varian Trilogy with FFF machine. The dose points such as