VISCOSITY REDUCTION PROCESS OF HYDROXY PROPYL METHYL CELLULOSE

This paper introduces the scheme to reduce Hydroxy Propyl Methyl Cellulose (HPMC) of high viscosity ~ 4 Pascal. Second to low viscosity ~ 0.004 Pascal. Second. The application involved was in the manufacture of raw material HPMC for capsule manufacturing. The process parameters considered for the viscosity reduction process were quantity of feed, batch cycle time, temperature of the operation and quantity of HCl gas. After optimization of these process parameters, HPMC of ~4 Pascal. Second was reduced to HPMC of ~0.004 Pascal. Second.