Biotechnological Preparations: Peculiarities of Structure Properties and Methodology of Teaching their Pharmacology to Students of Profile Higher Educational Instructions

Our century is characterized by innovative technologies inculcation that is used in all spheres of life including pedagogies promoting the student's acquaintance with the modern medical and pharmaceutical technologies. For the improvement of pharmacology teaching quality it is necessary to upgrade the pedagogic technologies to the students of medical and pharmaceutical faultiest. With that purpose the biotechnological drugs are included into the pharmacology program for the students in medical and pharmaceutical facilities. Material and methods. Those drugs are obtained by biological effects by using means of special technological processes like cell engineering, hybrid technology, engineering enzymology, engineering immunology and others. The biotechnological drugs include certain antibiotics, hormone and vitamin drugs, drugs of blood, cytokines, immunomodulators, enzymes, lipids, polysaccharides, and monoclonal antibodies. Biotechnological drugs differ from the drugs of chemical synthesis not only by technology of receipt but also by considerable molecular mass, complexity of structure of the proteins in the space, definite isoforms correlation, instability of molecule and other properties. But the biotechnological drugs have the high value connecting with the complicated technological process. It is impossible to create the analogue of biotechnological product by chemical synthesis. When there is wish to reproduce the biotechnological drug the biosimilar may be obtained. It will be investigated in preclinical experiments (in vitro, in vivo) including pharmacokinetics and then in the clinical traits. In Ukraine the biosimilars exchange is regulated by pharmacovigilance system. In the lectures and the practical lessons the pharmacology of the biotechnological drugs is considered by the topics “Hormonal drugs”, “Vitamine drugs”, “Antibiotics” and during the learning of drugs pharmacology that influence on the systems and organs, antineoplastic agents, immunomodulating agents. Conclusions. Teaching students the peculiarities of biotechnological drugs properties promotes the competent approach to the pharmacology study at medical and pharmaceutical facilities. The competent approach to the structure of the pedagogical process of students of medical and pharmaceutical faculties, aimed at improving professional orientation, meets the needs of the healthcare sector, and will contribute to the modernization of the creative and professional activities of future specialists.