SYNTHESIS, SPECTRAL CHARACTERIZATION AND ANTIFUNGAL STUDIES ON LANTHANUM (III) AND PRASEODYMIUM (III) COMPLEXES WITH N2O2DIAZADIOXAMACROCYCLES

A novel series of N2O2diazadioxamacrocyclic complexes of type [Ln(mac)Cl3] has been synthesized via the condensation reactions of a 3-(phenyl/substituted phenyl)-4-amino-5-hydrazino-1,2,4-triazoles with salicylaldehyde and 1,4-dibromobutane in the presence of lanthanum(III) chloride and praseodymium(III) chloride in ethanol. All the newly synthesized compounds were characterized by elemental analysis, electronic absorption, IR, 1HNMR. The particle size of the complexes have been calculated from XRD spectral using Debye-Scherrer formula and these are found to be in 29-31 nm range. In order to evaluate the biological activity of Schiff bases and to assess the role of Ln(III) and Pr(III) metal on biological activity, the hydrazine triazole Schiff bases and their lanthanide complexes have been studies for in vitro antifungal activity against Fusariumoxysporum, CurvularialunataandColletotrichumfalcatum.