Cerebellar hypoplasia in an Azawakh dog: A case report

In this case report, the nine-month-old male Azawakh dog was observed to ataxia, uncoordinated move­ments, difficulties in walking and standing, intensive head tremors, trouble evacuating and eating. It was determined mild cerebellar hypoplasia at the magnetic resonance imaging. Symptomatic treatment was started with glu­cocorticoids, vitamin B1, B6and diazepam. But these drugs had no effect on symptoms and the dog died after three weeks. It described a macroscopic cerebellar reduction in the necropsy and cerebellum and granular cell hypoplasia in histopathologically. Immunohistochemically, the atrophy of neuronal cells showing positive staining with anti-GFAP antibody and vacuolar degeneration were identified. Based on clinical findings, MR imaging, histopathological and immunochemical findings, cerebellar hypoplasia was diagnosed in the dog and this study is the first case detected in the Azawakh dog.