Venous Sinus Thrombosis in A Preterm Male Neonate with Elevated Anti-Phospholipid Antibodies: A Case Report

Background: Cerebral venous sinus thrombosis (sinovenous) (CSVT) is a rare and yet an important cause of morbidity and mortality in neonates. The Canadian registry quotes an incidence of 41 per 100,000 newborns per year. Cerebral sinovenous thrombosis is rarely reported in preterm infants. Although it is a potentially devastating condition with poor neuro developmental outcome, the risk factors are still poorly understood and the awareness to diagnose this condition is lacking. Males are at higher risk for both arterial ischemic stroke and for the sinovenous thrombosis. Case Report: We report a preterm, male neonate with right transverse venous sinus thrombosis, who had perinatal risk factors and elevated antiphospholipid antibodies on follow up. No other known risk factors for thrombosis were identified. High levels of anti phospholipid antibodies in this infant, could have possibly lead to venous sinus thrombosis in neonatal period.