Effect of the MNRI Reflex Neuromodulation on the QEEG and Neurotransmitters of Children Diagnosed with Cerebral Palsy

This study provides data on MNRI and its neuromodulation effect on: 1) the brain wave spectrum of children with cerebral palsy (CP), 2) regulation of their neurotransmitters, and 3) changes in reflex development level evaluated by the MNRI reflex assessment. Seventy-eight individuals aged 2-19 years (M ± SD=7, 65 ± 4, 85) diagnosed with cerebral palsy were included in the Study Group and received an 8-day of Reflex Neurosensorimotor Integration (MNRI) treatment program. The evaluative methods of effects of Reflex patterns treatment program included: The MNRI Reflex Assessment (Reflex Maturity Scaling) on each of the individuals in the study group before and after the rehabilitation program. This group received the MNRI Reflex sensory-motor neuromodulation rehabilitation program. Brain mapping QEEG records analysis (phases 1, 2, 3) done before and after rehabilitation with the MNRI. Neurotransmitters Analysis (the test utilized the #9123 extended panel including 12 neurotransmitters, particularly, analysis of epinephrine, norepinephrine, DOPAC, dopamine, GABA, glutamate, serotonin, 5-HIAA, PEA, glycine, histamine and taurine and some other [1-3]. All three evaluation methods showed substantial positive changes in children with CP in corresponding areas after the MNRI treatment, particularly: 79.5% (62 out of 78) children displayed a reorganization of spontaneous brain electrical activity noted in an increase in brain frequency in range of alpha waves and a decrease in hi-beta activity in areas of the parietal and temporal cortex. This can be interpreted as a positive and stable regulatory effect of the MNRI program on neuromotor disorders causing deficits in the central nervous system. This may be connected with the positive and stable therapeutic effect of the MNRI method on motor disorders that originate in the central nervous system. The neurotransmitters analysis showed improvement in a) regulating effect, b) enhancement of stress regulation (taurine decrease); c) an antiinflammatory effect (improving cytokinesis), d) restoration tendency for nerve fibers (serotonin as a modulator for glutamate), d) hormonal changes supporting muscle tone regulation and motor control support. 66.7% (26 out of 30) reflex patterns showed significant improvement. This study demonstrated that the neurodevelopment and overall functioning of individuals with neuro deficits, such as the CP, are not static in pathology and can be significantly improved with MNRI tools presenting a form of neuromodulation treatment.