Tumour Metabolism: An Emerging Therapeutic Target for Cancer Treatment

Malignant cells are highly proliferative in nature and display invasion and metastatic properties. Hence, they need rapid energy and huge amount of macromolecules for their development and progression. They fulfil their energy and macromolecular demands either by speeding up/down or switching on /off the various metabolic pathways. Therefore, altered tumor cell metabolism is considered as one of the emerging hallmark features of cancer cells. Most of the cancerous cells usually show dependency on glycolysis, glutaminolysis and lipid biosynthetic pathways.