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Journal: International Journal of Pharmaceutical Sciences and Medicine (IJPSM) (Vol.6, No. 6)

Publication Date:

Authors : ; ; ; ; ;

Page : 15-27

Keywords : Niosomes; non-ionic surfactants; ionic drug carriers; bioavailability; encapsulated; multilamellar;

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Niosomes are non-ionic surfactant-based multilamellar or unilamellar vesicles in which an aqueous solute solution is completely encapsulated by a membrane formed by surfactant macromolecules organised as a bilayer. Because vesicles are made up of a bilayer of non-ionic surface-active substances, the term "Niosomes" was coined (non-ionic surfactants). Niosomes are an unique drug delivery technology that encapsulates the medication in a vesicle. Ionic drug carriers are hazardous and inappropriate, whereas niosomal drug carriers are less dangerous. Niosomes do not require any specific handling or storage conditions.Niosomes have shown to be a promising drug carrier, with the potential to minimise medication side effects and improve therapeutic efficacy in a variety of disorders. Drug insolubility, instability, limited bioavailability, and fast degradation are all issues that niosomes address. The benefits, preparations, assessment, and medicinal uses of niosomes are discussed in this review article.

Last modified: 2021-06-06 23:30:13