Histomorphological Spectrum of Prostatic Lesions in Yobe State, in North-Eastern Nigeria: A Preliminary Report

BACKGROUND: Lesions of the prostate including prostate cancer are globally recognized as common causes of morbidity and mortality in the men population. The incidences are increasing, Their effects on the men????????s quality of life cannot be over emphasized. OBJECTIVES: The objectives of our study was to review the histology results of prostatic specimens in Yobe state. particularly, the histo-morphological spectrum of these lesions in short term (preliminary report)., METHODS: The results of prostatic specimens that were examined between October 2016 and September 2019 in the two departments of Histopathology of Yobe state University Teaching Hospital (YSUTH) and Federal Medical Centre Nguru were retrospectively reviewed and analyzed using SPSS version 20. RESULT: A total of 287 specimens were examined, out of which 161 (56.1 %) specimens were reported in YSUTH. Nodular hyperplasia with or without associated prostatitis was the commonest prostatic lesion (237 specimens, 82.6 %) among all the specimens. Adenocarcinoma was the only malignant type of lesion seen in 49 specimens (17.1 %), mainly in the age group of 70-79yrs. More than half (53.1 %) of these Adenocarcinoma were Poorly differentiated. Prostatic Intra-epithelial Neoplasia was seen in one specimen only. CONCLUSION: Although more benign lesions were observed than malignant, but most of the malignancies were poorly differentiated with potential bad prognosis. Hence, there is need to strengthen awareness campaign to allow for early detection of these lesions.