Letter to the Editor and Global Public: Lockdown Block Efficiency Equivalent Devices for COVID-19 Pandemic

To date, the only successful strategy for blocking COVID-19 is by a large-scaled lockdown at the population level. China, Thailand, and Vietnam have successfully taken this strategy to control their pandemic. The root cause is possibly the RNA coronavirus evolution pattern, if the SARS-VOR-2 can continuously get fresh human bodies as relay hosts, they will mutate to the acceleration speed of spreading among people. If we cut down their transmission pathway by a high-efficiency method such as lockdown, they will mutate to exploit the already resided hosts, such as compete well inside the host with other in vivo mobile genetic elements and become less transmissible. According to China????????s hand-on experience, both SARS in 2003 and SARS-VOR-2 today will finally wane or mutate to a less virulent strain after 6-12 months of a large-scaled lockdown. This is somewhat like the pneumonia calcification process, just happens at a population level instead of individual human lungs.