Osseointegration of Dental Implants Bioactivated with Stem Cells and Prp-an invivo Study

STATEMENT OF PROBLEM: Many implant systems propose a delayed loading protocol for loading of implants. This waiting period of osseointegration of implants of 3 ???????? 6 months is often cumbersome to both the dentist and the patient. PURPOSE: This study proposes to compare the effect of mesenchymal cells and PRP on reducing or eliminating the waiting period of osseointegration. MATERIALS AND METHODOLOGY: 5 Healthy subjects were selected based on having more than one missing teeth in maxillary or mandibular arches, preferably both sides of arches. After CBCT and other hematological tests, implants were placed following standard protocols with PRP on one side and with the use of stem cells on the other side. Implants were placed and surgical protocol followed. The insertion force was maintained at 35N.Resonance frequency analysis (RFA) was done with Ostell ISQ values were analyzed. RESULTS: A Pair T Test was performed and significant difference was found in the mean RFA at 8th and 10th week on stem cell side suggestive of early osseointegration. CONCLUSION: It was concluded that the use of mesenchymal cells reduces the time interval for loading of implants from 12 weeks to 8 weeks.