Adenocarcinoma: Morphological & Topographical spectrum: a two year analysis

Aim To study of adenocarcinoma of various sites and classify them into morphological categories according to International Classification of Diseases for Oncology (ICD-O, Third edition). Background The word cancer is enough to strike fear in the heart of any man because it is this one menace that researchers have been unable to curb, It is for this reason that many ideas are thought of and pursued with the hope of unraveling this mystery. In keeping with this a study delineating the morphological and topographical spectrum of adenocarcinoma was carried out in the Department of Pathology MGM Medical College and M Y Hospital Indore, MP, India. Material Methods A retrospective study of adenocarcinoma cases diagnosed during last 2 years, from January 2007 to December 2008 was carried out. ICD-O (3rdEd.) was used as reference to categorize the cases according to anatomical site and morphology. Results Total 325 cases were included, out of which, the maximum, i.e. 221 cases (68%) of Adenocarcinoma were found between third and fifth decades. The average for males was 48.1 years while for females was 47.8 years. The frequency of Adenocarcinoma was highest among those involving breast (56.50%), followed by those involving digestive system (30.24%). Regarding the topographical distribution of Adenocarcinoma, the maximum number of cases (26.07%) of Adenocarcinoma belonged to ICD-O category C-50 i.e. breast. Conclusion As far as the behavior pattern of the Adenocarcinoma was concerned, most of the cases in our study were invasive type. Hence keeping this in mind the topographical spectrum prevalent in the area and having a high index of suspicion can prove to be useful for early detection, treatment, improved survival rate and reduced mortality in such cases.