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A Short Synthesis of Carbazole Alkaloids Murrayanine and Mukonine

Journal: Chemical Methodologies (Vol.5, No. 4)

Publication Date:

Authors : ; ; ; ; ; ; ; ;

Page : 341-347

Keywords : Carbazole Alkaloids; Mukonine; Murrayanine; Buchard coupling;

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The short, easy and total synthesis of Murrayanine (1),  Mukonine (2), carbazole alkaloids were elaborated, based on a regioselective buchwald coupling of methyl 4-bromo-3-methoxybenzoate  with aniline and successive transformation into the corrsponding carbazole alkaloids by  oxidative coupling followed by cyclization of the phenyl and aryl rings.  

Last modified: 2021-06-27 22:47:33