Correlation between Hyperuricemia and Albuminuria in Type 2 Diabetes Mellitus Patients in Jaipur, Rajasthan

Background- Diabetes mellitus comprises a group of metabolic disorders characterized by hyperglycaemia as a consequence of defects in insulin secretion, action, or both. The chronic hyperglycemia of diabetes is associated with long-term damage, dysfunction, and failure of different organs, especially the eyes, kidneys, nerves, heart, and blood vessels. Type 2 Diabetes is associated with a number of complications which develop as a result of an interplay between a sustained hyperglycaemic state, low grade inflammation and increased atherogenesis. There are broadly two types of complications Microvascular complications which include: Retinopathy, Neuropathy, Diabetic Kidney Disease and Macrovascular complications include- Coronary Artery Disease, Peripheral Artery Disease, Cerebrovascular disease. Elevated uric acid levels can result from increased generation or decreased elimination. Increased generation, in turn, can be caused by ingesting a purine-rich diet or alcohol, by certain genetic disorders (such as the Lesch-Nyhan syndrome), and by increased turnover of cells (such as in myeloproliferative diseases or tumor lysis syndrome). There is a relation between microalbuminuria and decreased glomerular filtration rate with beyond normal increased serum uric acid levels in type 2 DM patient. Materials and Methods- This study was done under Deparment of General Medicine of teritary care teaching hospital. The duration of this study was two years. Total number of One-hundred Twenty-four Patient’s data were collected under this study. Collected data were analysed by using Microsoft Excel 2018. Conclusion- The study conducted is a hospital-based study which included predominantly the rural diabetic population of the state of Rajasthan. We showed in this study that high serum uric acid levels were significantly associated with albuminuria. Hyperuricemia is easily diagnosable and is a common finding in these patients.