Premature Greying: Role of Vit D3, Vit B12 and S.Ferritin

Background: Canities or greying of hairs is a physiologic process that occurs with age in both men and women. A role of various nutritional deficiencies has been postulated. . Aim: To determine the levels of Vit D3, Vit B12 and S. ferritin in patients with premature graying of scalp hairs. Materials and methods: A total of 60 patients with age less than 30 years and greater than 30 % graying of scalp hairs were enrolled for the study. They were investigated for various parameters like S. vit D3, S. vit B12 and S. ferritin after taking informed consent. Result: The mean S. ferritin, S. Vit B12 and S. ferritin levels were significantly low in study group as compared to the control group. There was significant Vit D3 insufficiency in the study group as compared to the control group (60 % versus 36.67 %). Combined Vit D3 and Vit B12 deficiency was present in 13.33 % of patients and triple deficiency was present in 8.33 %. Conclusion: Our study suggests significant association between nutritional deficiency and canities. Due to smaller study group and observed pandemic with Vit D3 deficiency larger trials are required to validate the results.