Impact of (APZ) Alprazolam on its user in Sidhi District of Madhya Pradesh, India

The study aims to evaluate APZ effected on blood metabolites, RBC (Red blood cells) membrane and nitric oxide (NO) levels on long term use by human volunteers. A total of (10) tem volunteers taken for study out of which (5) non APZ users (Gr-I) and Rest (5) is long term APZ user (Gr. II) served as a test sample. Biochemical studies were conducted with plasma and RBC membrane of both two groups (I and II) Result of this study revealed that the concentration of glucose, cholesterol and lipoprotein LDL-C were decrease and in contrast the concentration of triglycerides, lipoprotein (HDL-C& VLDL-C) and Nitrate were increased in plasma of group II when compared with group I.