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Age aspect of adaptive response of the central nervous system in the state of emotional pain

Journal: Medicni perspektivi (Vol.19, No. 4)

Publication Date:

Authors : ;

Page : 12-17

Keywords : spontaneous behavioral activity; spatial memory; unsaturated fatty acids; hippocampus; neocortex;

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The formation of higher adaptive response in the postoperative period was investigated in expe¬riments on rats of two age groups. It was found inhibition of the orientation-motor and emotional activity in young (5-6 months) and old rats (20-24 months) with the greatear effect in animals of the first age group. In young rats the inhibition of spatial memory was observed ? number of food-getting depleted reactions decreased by 28%. Cognitive deficit was accompanied by opposite changes in the content of free unsaturated fatty acids (C18: 2.3), respectively to age features: decreased by 46% in the cortex of young rats and increased by 2.5-fold in the hippocampus of old animals.

Last modified: 2014-12-22 21:02:23