Prevalence of Class A - Carbapenemases Producing Enterobacteriaceae in Clinical Isolates in MBS Hospital, Kota, Rajasthan

AIM: The aim of this study was to determine the prevalence Class-A carbapenemases producing enterobacteriaceae in clinical isolates in MBS Hospital, Kota. MATERIAL AND METHODS: The study period was from September 2018 to March 2019. The samples which were imipenem resistant were tested for carbapenemase production by Modified Hodge Test. RESULT: Out of total 100 isolates of enterobacteriaceae, 21 were imipenem resistant of which 17 were carbapenemase producing as detected by Modified Hodge Test. Most common isolates were E. coli and Klebsiella. CONCLUSION: The frequency rate of carbapenemase producing Enterobacteriaceae is increasing many folds. Early identification of carbapenemase producers in clinical infections is immportant to prevent development of hospital-based outbreaks carbapenemase producers. . Implementations of appropriate strategies with Over-the-counter use of antibacterial drug should be checked to limit the spread of carbapenem resistant Enterobacteriaceae.