Anti Microbial Susceptibility Patterns of Patients with Urinary Tract Infection in a Tertiary Care Hospital, Mangalore

Introduction Urinary tract infection is a common disease, a clinician comes across and is a major public health problem in terms of morbidity and financial costs incurred. There may be difference between geographical areas in the prevalence of the most common organisms responsible for UTI and susceptibity patterns may vary. Methods This study is to obtain the data regarding the prevalence and antibiotic sensitivity patterns in Father Muller medical college based on the data collected from urine cultures received at microbiology department from April 2018 to October 2018. This is an observational study using urine culture sensitivity reports analysed retrospectively. Results A total of 4733 urine samples were analysed, out of which 29.4 % had significant growth that is a total of 1392 identified pathogens were analysed. E. coli (36.8 %) was the most common pathogen responsible for UTI followed by Klebsiella (18.5 %), Enterococci (9.77 %), Staphylococci (8.54 %) and pseudomonas (7.18 %) in order. E coli was resistant to ampicillin in 78 % of cases and cephalosporins in 70 % of cases Klebsiella is resistant to ampicillin in 88.2 % of cases and cephalosporins in 60 % of cases. E. coli is resistant to ciprofloxacin and levofloxacin in 57.4 % and 58.4 % of cases. Among klebsiella cultures 48.1 % of growths were resistant to ciprofloxacin and 47.5 % of cases to levofloxacin. Among enterococci group fluoroquinolones are resistant up to 60 % of cases. Staphylococci have good sensitivity to pencillins and cephalosporins compared to fluoroquinolones. Conclusion Uropathogens monitoring and their antibiotic sensitivity profile is needed on frequent basis according to the regional need, so that appropriate evidence based management of UTI empirically is possible till the urine cultures are available.