Syntheses, Characterization and Biological Activity of Nickel Chalcone Complexes

The Nickel (II) chalcone complexes were prepared by refluxing Nickel sulphate heptahydrate with different substituted chalcones in methanoic medium. The chalcones were prepared with different aromatic aldehydes like Benzaldehyde, Hydroxy benzaldehyde, Nitro benzaldehyde and Chloro benzaldehyde. The synthesized Nickel complexes were characterized by different spectral techniques. The elemental analysis and IR spectral studies of the complexes revealed that the chalcone derivatives are bidentate ligand. The thermal study explained the stability of complex and its decomposition. Magnetic studies suggested the paramagnetic behavior of the complexes. UV spectral studies suggest that the complexes are in octahedral geometry. Conductance measurements suggest that all complexes are non-electrolyte in DMF. The synthesized ligand and metal complexes were screened for their antibacterial activity against E. coli and staphylococcus aureus bacterial strains and for antifungal activity against P. notatum and Candida.