Evaluation of in vitro Anti-inflammatory Activity, Total Phenolic and Flavonoid Content of Methanol Extract of Leaves of Acmella paniculata

Acmella paniculata is a folk medicinal plant of Mizoram used by the folk medicinal practitioners to recuperate their different ailments. The current experiment was designed to investigate anti-inflammatory potential of methanol extracts of leaves of Acmella paniculata along with total phenolic content and total flavonoids content. Evaluation of total phenolics and flavonoids content showed presence of natural antioxidant agents. Inhibition of protein determination method was performed to assess in extract possess potent antioxidant property and polyphenol compounds present may help in radical related problem diseases. In-vitro anti-inflammatory activity study gives anti-inflammatory property when compared with standard diclofenac sodium. It has a good capability of controlling the production of auto antigen and therefore inhibit the denaturation of proteins.