Chronicle of Central Giant Cell Granuloma

Central giant cell granuloma (CGCG) earlier was known as the giant cell tumor of bone (GCT). Many investigators believe CGCG as a different entity and studied it extensively to suggest the differentiation between the two lesions based on histomorphological details. Many of them have studied the giant cells of both lesions in the broad range including the size, number of nuclei and distribution pattern. This review aims to discuss the evolution of CGCG as a separate lesion along with its clinical and histopathological details.