Correlation between the Severity Level of Maxillofacial Trauma with Prealbumin Level in Patient Treated with Open Reduction Internal Fixation Followed by Intermaxillary Fixation

Introduction: Nutritional status is a factor that must be critically evaluated in candidates for oral surgery patients, who will be carried out open reduction internal fixation (ORIF) followed by intermaxillary fixation (IMF) because it will disrupt the patient's normal diet. Prealbumin (PAB) is a biomarker that is sensitive to malnutrition. The purpose of this study was to analyze differences in prealbumin levels before and after ORIF and IMF and the relationship between prealbumin levels and MFISS scores in maxillofacial trauma patients. Methods: Analytical observational study with a cross-sectional approach was carried out in patients with maxillofacial trauma that will be treated with ORIF and IMF at Hasan Sadikin Hospital, Bandung, Indonesia on periode October 2017- March 2018. The assessment of MFISS scores performed one day before the operation and the retrieval of the blood sample examination material taken a day before the operation and postoperatively at day 2 and 14. The data collected then analyzed by using Wilcoxon test to determine prealbumin levels before surgery and postoperative, while Chi Square test used to fill MFISS scores with pre and postoperative prealbumin levels. Results: From 16 maxillofacial trauma patients, 3 patients with minor category, 4 patients with moderate category, 3 patients with serious category, and 6 patients with severe category. Analysis of the correlation between preoperative prealbumin levels and postoperative days 2 and 14 with p-values of 0.033 and 0.191, respectively. Correlation analysis between MFISS score and preoperative prealbumin level, on day 2 and day 14 after operation with p-value 0.145; 0.017; and 0.325, respectively. Conclusion: There was a significant difference between prealbumin levels of preoperative and postoperative day 2. Furthermore, there was a significant correlation between the severity of maxillofacial trauma based on MFISS scores with prealbumin levels postoperatively on day 2.