Effect of Non-Hormonal Treatment on Uterine Leiomyoma

AIM: To evaluate the efficacy of Non-Hormonal drugs on Uterine Leiomyoma METHOD: The study was conducted on sixty women of age 20-50 yrs with Leiomyoma. All cases were randomly divided into three groups, Group 1 received 25mg Mifepristone once daily, Group 2 received Ormeloxifene 60mg biweekly and group 3 received Tripterygium wilfordii 30mg with Vitamin D 1000IU twice daily orally for 6 months. The efficacy of the drugs were analyzed by comparing the pre- treatment and post-treatment reduction in size of Leiomyoma, Pictorial blood assessment chart (PBAC), Visual Analogue Score (VAS), Haemoglobin level and Endometrial Thickness (ET). RESULT: A statistically significant reduction in PBAC score in group1 (p